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File:Psoriasiform epidermal hyperplasia and band-like lymphocytic infiltrates in papillary dermis.jpg

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Summary

Description
English: Biopsy of a yaws lesion of a 10-year-old boy from Cotabato Province. Low-power view; for high-power view, see File:Moderately dense infiltrate of plasma cells and lymphocytes in the papillary dermis. See File:Large, “moist cauliflower” papillomas on left axilla.jpg for macroscopic view of the yaws lesion from which the biopsy was taken.

From original CC-BY report: "Histopathologic findings of yaws papilloma

A skin punch biopsy of the papilloma on the left axilla of the index case (Case 1) was performed by the principal investigator in the Rural Health Center 2 weeks post-treatment. The specimen was processed in the Philippine General Hospital and read by a dermatopathologist of the Division of Dermatology.

The biopsy showed psoriasiform epidermal hyperplasia and band-like lymphocytic infiltrates in the papillary dermis, with thickening of the basement membrane. There were moderately dense infiltrates of plasma cells and lymphocytes in the papillary dermis. The histopathologic diagnosis was lichenoid psoriasiform dermatitis with plasma cells. These findings were consistent with yaws "
Date
Source (30 January 2020). "Yaws in the Philippines: first reported cases since the 1970s.". Infectious diseases of poverty 9 (1): 1. DOI:10.1186/s40249-019-0617-6. PMID 31996251.
Author

Study authors, except for first five macro photographs, which are courtesy of Dr. Camille Toledo:

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Date/TimeThumbnailDimensionsUserComment
current19:05, 5 April 2020Thumbnail for version as of 19:05, 5 April 2020709 × 473 (137 KB)HLHJUploaded a work by Study authors, except for first five macro photographs, which are courtesy of Dr. Camille Toledo: Large, “moist cauliflower” papillomas on left axilla.jpeg Yaws papillomas on axilla significantly reduced in size 2 weeks and completely resolved 3-and-a-half months after one-dose azithromycin was taken.jpeg Papulosquamous plaque and yellow-crusted nodules of secondary yaws on the leg (far view and close-up).jpeg Leg and anterior trunk 3 months post-treatment; Atrophic scars...

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