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Extended-confirmed-protected edit request on 30 September 2024

[edit]

Changing this:

"A low level of blood lymphocytess may result from the virus acting through ACE2-related entry into lymphocytes.[157]"

to the following:

"COVID-19 can lower lymphocyte presence in blood and can be a valuable prognostic marker. This lymphopenia may be caused by several factors, including at least lymphocyte trafficking (especially to the lungs and large bowel)[add1][add2] and possibly direct infection through the ACE2 receptor.[157]"

[add1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9050483/

[add2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8473169/

The reason for this change is that there is well-recorded evidence as above that the lymphopenia is not only due to direct infection, and a consensus is not clear on what the primary cause of lymphopenia in COVID-19 is. There's clear cut evidence of it for trafficking, but the direct infection causing apoptosis is less clear but commonly posited in research. Noahkahn (talk) 07:05, 30 September 2024 (UTC)[reply]

This article as a YouTube "Information Panel"

[edit]

the first two sentences of the lede is used extensively as a so-called "Information Panel," (which also provides a link to the article) on YouTube videos that discuss Covid-19.

As this garners considerable traffic and even more viewer impressions on YouTube, it seems inappropriate to include the first known case being in Wuhan within that very brief opening. Similarly, the article could say within the first two sentences that viralogists from Wuhan, China were the first to publicly identify the virus. (To be clear, I propose neither be included in the first two sentences of the lede and am just mentioning that to demonstrate the potential implications for framing such minutiae in portion of the lede that gets used for fact-checking purposes). The importance of Wuhan, China to the article of Covid-19 should be lower in the lede, or arguably not included in the lede at all.

For the sake of both prioritizing the most important facts within the article, as well as maintaining appropriate brief descriptions used by off-site platforms, I propose that the second sentence should be changed to discuss the severity, ie the spread and lethality, of the virus.

If you have opposing or alternative thoughts on the first two sentences, I am interested in hearing them. 2601:5CF:8000:6B60:4010:2BF9:AAE6:C475 (talk) 16:00, 1 October 2024 (UTC)[reply]

thank you for posting--Ozzie10aaaa (talk) 17:45, 1 October 2024 (UTC)[reply]