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Caetano Reis e Sousa

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In this Portuguese name, the first or maternal family name is Pacheco Pais and the second or paternal family name is dos Reis e Sousa.
Caetano Reis e Sousa
FRS FMedSci
Born
Caetano Maria Pacheco Pais dos Reis e Sousa

1968 (age 55–56)[3]
Lisbon, Portugal[3]
EducationAtlantic College
Alma materImperial College London (BSc)
University of Oxford (DPhil)
AwardsEMBO Member (2006)[1]
Louis-Jeantet Prize for Medicine (2017)
Scientific career
FieldsImmunology[2]
InstitutionsFrancis Crick Institute
Imperial College London
Imperial Cancer Research Fund
National Institute of Allergy and Infectious Diseases
ThesisPhagocytosis of antigens by Langerhans cells
Doctoral advisorJonathan Austyn
Websitewww.crick.ac.uk/research/labs/caetano-reis-e-sousa

Caetano Maria Pacheco Pais dos Reis e Sousa (born 1968)[3] is a Portuguese scientist who is a senior group leader at the Francis Crick Institute[2][4][5][6] and a professor of Immunology at Imperial College London.[7]

Education

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Reis e Sousa was educated at Atlantic College in Wales,[6] Imperial College London (BSc) and the University of Oxford where he was awarded a Doctor of Philosophy degree in 1992 for research on dendritic cells, and the phagocytosis of antigens by Langerhans cells supervised by Jonathan Austyn.[8]

Career and research

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After working as a postdoctoral researcher at the National Institute of Allergy and Infectious Diseases (NIAID) in the United States, with Ronald Germain, he joined the Imperial Cancer Research Fund (ICRF) in 1998.[9] He headed the Immunobiology Laboratory which became part of the Francis Crick Institute in 2015.[9] He is also a professor of Immunology at Imperial College London[10][7] and honorary professor at University College London (UCL) and King's College London.[9]

Caetano's research centres on the mechanisms involved in sensing infection, cancer and tissue injury.[9] He has helped to define the cells and pathways involved in innate immune detection of RNA viruses, fungi and dead cells.[9][11][12][13]

Awards and honours

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Reis e Sousa was elected a Fellow of the Royal Society (FRS) in 2019, and is also a Fellow of the Academy of Medical Sciences (FMedSci), a member of the European Molecular Biology Organization (EMBO)[1] and was made an Officer of the Order of Sant'Iago da Espada by the Government of Portugal in 2009.[9] He was awarded the Louis-Jeantet Prize for Medicine in 2017.[3]

References

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  1. ^ a b Anon (2006). "Caetano Reis e Sousa". people.embo.org. European Molecular Biology Organization.
  2. ^ a b Caetano Reis e Sousa publications indexed by Google Scholar Edit this at Wikidata
  3. ^ a b c d "Caetano REIS E SOUSA". jeantet.ch. 4 October 2017.
  4. ^ "Caetano Reis e Sousa: Immunobiology Laboratory". crick.ac.uk.
  5. ^ "Researchers: Caetano Reis e Sousa". crick.ac.uk.
  6. ^ a b Bashyam, Hema (2008). "Caetano Reis e Sousa: harnessing DC power". The Journal of Experimental Medicine. 205 (9): 1946–1947. doi:10.1084/jem.2059pi. ISSN 0022-1007. PMC 2526189. PMID 18762569.
  7. ^ a b "Professor Caetano Reis e Sousa". Imperial College London.
  8. ^ Reis e Sousa, Caetano Maria Pacheco Pais dos (1992). Phagocytosis of antigens by Langerhans cells (DPhil thesis). University of Oxford. OCLC 863542179. EThOS uk.bl.ethos.314901. Free access icon
  9. ^ a b c d e f Anon (2019). "Professor Caetano Reis e Sousa FMedSci FRS". royalsociety.org. London: Royal Society. Archived from the original on 24 April 2019. One or more of the preceding sentences incorporates text from the royalsociety.org website where:

    "All text published under the heading 'Biography' on Fellow profile pages is available under Creative Commons Attribution 4.0 International License." --Royal Society Terms, conditions and policies at the Wayback Machine (archived 2016-11-11)
  10. ^ Caetano Reis e Sousa publications from Europe PubMed Central
  11. ^ Diebold, S. S. (2004). "Innate Antiviral Responses by Means of TLR7-Mediated Recognition of Single-Stranded RNA". Science. 303 (5663): 1529–1531. Bibcode:2004Sci...303.1529D. doi:10.1126/science.1093616. ISSN 0036-8075. PMID 14976261. S2CID 33144196. Closed access icon
  12. ^ Kato, Hiroki; Takeuchi, Osamu; Sato, Shintaro; Yoneyama, Mitsutoshi; Yamamoto, Masahiro; Matsui, Kosuke; Uematsu, Satoshi; Jung, Andreas; Kawai, Taro; Ishii, Ken J.; Yamaguchi, Osamu; Otsu, Kinya; Tsujimura, Tohru; Koh, Chang-Sung; Reis e Sousa, Caetano; Matsuura, Yoshiharu; Fujita, Takashi; Akira, Shizuo (2006). "Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses". Nature. 441 (7089): 101–105. Bibcode:2006Natur.441..101K. doi:10.1038/nature04734. ISSN 0028-0836. PMID 16625202. S2CID 2270879. Closed access icon
  13. ^ Pichlmair, A.; Schulz, O.; Tan, C. P.; Naslund, T. I.; Liljestrom, P.; Weber, F.; Reis e Sousa, C. (2006). "RIG-I-Mediated Antiviral Responses to Single-Stranded RNA Bearing 5'-Phosphates". Science. 314 (5801): 997–1001. Bibcode:2006Sci...314..997P. doi:10.1126/science.1132998. ISSN 0036-8075. PMID 17038589. S2CID 44366096. Closed access icon
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