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List of steroid abbreviations

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The steroid hormones are referred to by various abbreviations in the biological literature. The purpose of this list is to give commonly used abbreviations for steroid hormones, with supporting references to the literature.

Table of abbreviations

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Trivial Name Abbreviation(s) Systematic Name
Cholesterol Chol[1] 5-cholesten-3beta-ol
Progestogens
Pregnenolone P5[2] or Preg[3] 3beta-hydroxy-5-pregnen-20-one
17α-Hydroxypregnenolone 17-OHP5[4] or 17P5[5] 3beta,17-dihydroxy-5-pregnen-20-one
Progesterone P4[6] or P[3] 4-pregnene-3,20-dione
17α-Hydroxyprogesterone 17-OHP4[4] or 17OHP[7] or 17P4[5] 17α-hydroxy-4-pregnene-3,20-dione
Allopregnanolone ALLO 5α-pregnan-3α-ol-20-one
Androgens
Androstenedione A4[8] or AE[9] 4-androstene-3,17-dione
4-Hydroxyandrostenedione 4-OH-A[3]
11β-Hydroxyandrostenedione 11βOHA4[10] or 11βOHΔ4[11] or OHA[12] 11β-Hydroxy-4-androstene-3,17-dione
Androstanediol Adiol[13] 3-beta,17-beta-Androstanediol
Androsterone AN[9] 3alpha-hydroxy-5alpha-androstan-17-one
Epiandrosterone EPIA[14] 3beta-hydroxy-5alpha-androstan-17-one
Adrenosterone AT[citation needed] 4-androstene-3,11,17-trione
Dehydroepiandrosterone DHEA[15] or DHA[16] 3beta-hydroxy-5-androsten-17-one
Dehydroepiandrosterone sulfate DHEAS[8] or DHAS[16] 3beta-sulfooxy-5-androsten-17-one
Testosterone T[4] 17beta-hydroxy-4-androsten-3-one
Epitestosterone epiT[17] 17alpha-hydroxy-4-androsten-3-one
5α-Dihydrotestosterone DHT[15] or 5α-DHT[18] 17beta-hydroxy-5alpha-androstan-3-one
5β-Dihydrotestosterone 5β-DHT[18] 17beta-hydroxy-5beta-androstan-3-one
11β-Hydroxytestosterone OHT[12] or 11β-OHT[19] 11beta,17beta-dihydroxy-4-androsten-3-one
11-Ketotestosterone 11-KT[20] 17beta-hydroxy-4-androsten-3,17-dione
Estrogens
Estrone E1[6] 3-hydroxy-1,3,5(10)-estratrien-17-one
Estradiol E2[4] 1,3,5(10)-estratriene-3,17beta-diol
Estriol E3[6] 1,3,5(10)-estratriene-3,16alpha,17beta-triol
Corticosteroids
Corticosterone B[7] or CORT[21] 11beta,21-dihydroxy-4-pregnene-3,20-dione
11-Deoxycorticosterone DOC[7] 21-hydroxy-4-pregnene-3,20-dione
Cortisol F[7] 11beta,17,21-trihydroxy-4-pregnene-3,20-dione
11-Deoxycortisol S[22] 17,21-dihydroxy-4-pregnene-3,20-dione
Cortisone E[7] 17,21-dihydroxy-4-pregnene-3,11,20-trione
18-Hydroxycorticosterone 18OHB[23] or 18B[24] 11beta,18,21-trihydroxy-4-pregnene-3,20-dione
1α-Hydroxycorticosterone 1α-B[25] 1alpha,11beta, 21-trihydroxy-4-pregnene-3,20-dione
Aldosterone A[7] or ALDO[26] 18,11-hemiacetal of 11beta,21-dihydroxy-3,20-dioxo-4-pregnen-18-al

References

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  1. ^ Needham D, McIntosh TJ, Evans E (1988). "Thermomechanical and transition properties of dimyristoylphosphatidylcholine/cholesterol bilayers". Biochemistry. 27 (13): 4668–73. doi:10.1021/bi00413a013. PMID 3167010.
  2. ^ Henson MC, Pepe GJ, Albrecht ED (1987). "Transuterofetoplacental conversion of pregnenolone to progesterone in antiestrogen-treated baboons". Endocrinology. 121 (4): 1265–71. doi:10.1210/endo-121-4-1265. PMID 3653027.
  3. ^ a b c Spinola PG, Marchetti B, Mérand Y, Bélanger A, Labrie F (1988). "Effects of the aromatase inhibitor 4-hydroxyandrostenedione and the antiandrogen flutamide on growth and steroid levels in DMBA-induced rat mammary tumors". Breast Cancer Res. Treat. 12 (3): 287–96. doi:10.1007/BF01811241. PMID 3147727. S2CID 2197068.
  4. ^ a b c d Martikainen H, Rönnberg L, Ruokonen A, Vihko R (1985). "Testicular responsiveness to hCG before and after long-term antiestrogen treatment in oligozoospermic men". J. Steroid Biochem. 23 (5A): 651–5. doi:10.1016/0022-4731(85)90017-2. PMID 4079381.
  5. ^ a b Miura T, Higuchi M, Ozaki Y, Ohta T, Miura C (2006). "Progestin is an essential factor for the initiation of the meiosis in spermatogenetic cells of the eel". Proc. Natl. Acad. Sci. U.S.A. 103 (19): 7333–8. Bibcode:2006PNAS..103.7333M. doi:10.1073/pnas.0508419103. PMC 1464341. PMID 16651536.
  6. ^ a b c Raimondi SG, Olivier NS, Patrito LC, Flury A (1989). "Regulation of the 3 beta-hydroxysteroid dehydrogenase activity in tissue fragments and microsomes from human term placenta: kinetic analysis and inhibition by steroids". J. Steroid Biochem. 32 (3): 413–20. doi:10.1016/0022-4731(89)90215-X. PMID 2523011.
  7. ^ a b c d e f Sippell WG, Dörr HG, Bidlingmaier F, Knorr D (1980). "Plasma levels of aldosterone, corticosterone, 11-deoxycorticosterone, progesterone, 17-hydroxyprogesterone, cortisol, and cortisone during infancy and childhood". Pediatr. Res. 14 (1): 39–46. doi:10.1203/00006450-198014010-00010. PMID 7360520.
  8. ^ a b Bridges NA, Hindmarsh PC, Pringle PJ, Honour JW, Brook CG (1998). "Cortisol, androstenedione (A4), dehydroepiandrosterone sulphate (DHEAS) and 17 hydroxyprogesterone (17OHP) responses to low doses of (1-24)ACTH". J. Clin. Endocrinol. Metab. 83 (10): 3750–3. doi:10.1210/jcem.83.10.5315. PMID 9768696.
  9. ^ a b Harding CF, Sheridan K, Walters MJ (1983). "Hormonal specificity and activation of sexual behavior in male zebra finches". Hormones and Behavior. 17 (1): 111–33. doi:10.1016/0018-506X(83)90021-1. PMID 6862388. S2CID 29041025.
  10. ^ Desprez D.1, Geraz E., Hoareau M.C., Melard C., Bosc P., Baroiller J.F. (2003). "Production of a high percentage of male offspring with a natural androgen, 11beta-hydroxyandrostenedione (11betaOHA4), in Florida red tilapia" (PDF). Aquaculture. 216 (1): 55–65. Bibcode:2003Aquac.216...55D. doi:10.1016/S0044-8486(02)00276-4. hdl:2268/76893.{{cite journal}}: CS1 maint: multiple names: authors list (link) CS1 maint: numeric names: authors list (link)
  11. ^ Govoroun M, McMeel OM, D'Cotta H, et al. (2001). "Steroid enzyme gene expressions during natural and androgen-induced gonadal differentiation in the rainbow trout, Oncorhynchus mykiss". J. Exp. Zool. 290 (6): 558–66. Bibcode:2001JEZ...290..558G. doi:10.1002/jez.1106. PMID 11748604.
  12. ^ a b D. Consten, E.D. Keuning, M. Terlou, J.G.D. Lambert, H.J.Th. Goos (2001). "Cortisol effects on the testicular androgen synthesizing capacity in common carp, Cyprinus carpio L.". Fish Physiology and Biochemistry. 25 (2): 91–98. doi:10.1023/A:1020538729104. S2CID 25897842.
  13. ^ Matthiesson KL, Stanton PG, O'Donnell L, et al. (2005). "Effects of testosterone and levonorgestrel combined with a 5alpha-reductase inhibitor or gonadotropin-releasing hormone antagonist on spermatogenesis and intratesticular steroid levels in normal men". J. Clin. Endocrinol. Metab. 90 (10): 5647–55. doi:10.1210/jc.2005-0639. PMID 16030154.
  14. ^ Pringle AK, Schmidt W, Deans JK, Wulfert E, Reymann KG, Sundstrom LE (2003). "7-Hydroxylated epiandrosterone (7-OH-EPIA) reduces ischaemia-induced neuronal damage both in vivo and in vitro". Eur. J. Neurosci. 18 (1): 117–24. doi:10.1046/j.1460-9568.2003.02734.x. PMID 12859344. S2CID 42753764.
  15. ^ a b Labrie C, Simard J, Zhao HF, Belanger A, Pelletier G, Labrie F (1989). "Stimulation of androgen-dependent gene expression by the adrenal precursors dehydroepiandrosterone and androstenedione in the rat ventral prostate". Endocrinology. 124 (6): 2745–54. doi:10.1210/endo-124-6-2745. PMID 2524377.
  16. ^ a b Dumitrescu A, Aberdeen GW, Pepe GJ, Albrecht ED (2007). "Developmental expression of cell cycle regulators in the baboon fetal adrenal gland". J. Endocrinol. 192 (1): 237–47. doi:10.1677/joe.1.06769. PMID 17210761.
  17. ^ Nuck BA, Lucky AW (1987). "Epitestosterone: a potential new antiandrogen". J. Invest. Dermatol. 89 (2): 209–11. doi:10.1111/1523-1747.ep12470564. PMID 3598212.
  18. ^ a b Perusquía M (2003). "Androgen-induced vasorelaxation: a potential vascular protective effect". Exp. Clin. Endocrinol. Diabetes. 111 (2): 55–9. doi:10.1055/s-2003-39229. PMID 12746753.
  19. ^ T.T. Wong, Y. Zohar (2003). "The involvement of gonadotropin receptors in sex reversal: expression, distribution and regulation of gonadal FSH and LH receptors in the gilthead seabream". Fish Physiology and Biochemistry. 28 (1–4): 179–180. Bibcode:2003FPBio..28..179W. doi:10.1023/B:FISH.0000030520.60240.cd. S2CID 11881590.
  20. ^ Lokman PM, Harris B, Kusakabe M, et al. (2002). "11-Oxygenated androgens in female teleosts: prevalence, abundance, and life history implications". Gen. Comp. Endocrinol. 129 (1): 1–12. doi:10.1016/S0016-6480(02)00562-2. PMID 12409090.
  21. ^ Thomas RM, Urban JH, Peterson DA (2006). "Acute exposure to predator odor elicits a robust increase in corticosterone and a decrease in activity without altering proliferation in the adult rat hippocampus". Exp. Neurol. 201 (2): 308–15. doi:10.1016/j.expneurol.2006.04.010. PMID 16750196. S2CID 43129386.
  22. ^ Reardon GE, Caldarella AM, Canalis E (1979). "Determination of serum cortisol and 11-deoxycortisol by liquid chromatography" (PDF). Clin. Chem. 25 (1): 122–6. doi:10.1093/clinchem/25.1.122. PMID 761348.
  23. ^ Auchus RJ, Chandler DW, Singeetham S, et al. (2007). "Measurement of 18-Hydroxycorticosterone During Adrenal Vein Sampling for Primary Aldosteronism". Journal of Clinical Endocrinology & Metabolism. 92 (7): 2648–51. doi:10.1210/jc.2006-2631. PMID 17473070.
  24. ^ Krishnan AV, Zhao XY, Swami S, et al. (2002). "A glucocorticoid-responsive mutant androgen receptor exhibits unique ligand specificity: therapeutic implications for androgen-independent prostate cancer". Endocrinology. 143 (5): 1889–1900. doi:10.1210/endo.143.5.8778. PMID 11956172.
  25. ^ Nunez S, Trant JM (1999). "Regulation of interrenal gland steroidogenesis in the Atlantic stingray (Dasyatis sabina)". J. Exp. Zool. 284 (5): 517–25. doi:10.1002/(SICI)1097-010X(19991001)284:5<517::AID-JEZ7>3.0.CO;2-S. PMID 10469989.
  26. ^ Kornel L, Smoszna-Konaszewska B (1995). "Aldosterone (ALDO) increases transmembrane influx of Na+ in vascular smooth muscle (VSM) cells through increased synthesis of Na+ channels". Steroids. 60 (1): 114–9. doi:10.1016/0039-128X(94)00016-6. PMID 7792795. S2CID 25467757.
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