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STK17A

From Wikipedia, the free encyclopedia
STK17A
Identifiers
AliasesSTK17A, DRAK1, serine/threonine kinase 17a
External IDsOMIM: 604726; HomoloGene: 55846; GeneCards: STK17A; OMA:STK17A - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004760

n/a

RefSeq (protein)

NP_004751

n/a

Location (UCSC)Chr 7: 43.58 – 43.65 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Serine/threonine kinase 17a is a protein that in humans is encoded by the STK17A gene.[3]

Function

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This gene is a member of the death-associated protein (DAP) kinase-related apoptosis-inducing protein kinase family and encodes an autophosphorylated nuclear protein with a protein kinase domain. The protein has apoptosis-inducing activity.[3]

In a recent study the gene (among others) shows a major role in centenarians longer lifespan.[4]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000164543Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ a b "Entrez Gene: Serine/threonine kinase 17a".
  4. ^ Garagnani P, Marquis J, Delledonne M, Pirazzini C, Marasco E, Kwiatkowska KM, et al. (May 2021). Tyler JK, Suh Y, Shuldiner AR (eds.). "Whole-genome sequencing analysis of semi-supercentenarians". eLife. 10: e57849. doi:10.7554/eLife.57849. PMC 8096429. PMID 33941312.

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.