Talk:Muscimol

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Toxicity

Article writes "Human deaths are rare, mainly occurring in young children, the elderly, or those with serious chronic illnesses."

But this is pointless since it obviously refers to mushroom poisoning, not poisoning with muscimol. The sentence implies that many people have experienced muscimol poisoning when in fact the number of people to ever have ingested pure muscimol will be quite low and no fatal case is presumably known.

Poisoning with mushrooms is complex and cannot be limited to muscimol action. In any case it should be discussed in the relevant mushroom articles, not here. 2001:9E8:32E2:2300:DD0D:3CCA:CA9:3E59 (talk) 14:15, 26 February 2023 (UTC)[reply]

Pharmacology

In the pharmacology section, the dosage information is incorrect. I noticed there has been much back and forth in regards to what to list with respect to mg of active ingredient vs. g of carrier fungus. From a biochemical perspective, this would be easily resolved by stating "dosage of 10-15 mg of muscimol, which is present in 5-10 g of fresh mushroom... Author recommends 8.5 mg of muscimol, which is stated to be present in as little as 1 g of dried mushroom." etc. This adds clarity between the subject chemical dosage and the carrier food/fungus amount to be injested, and given that the subject of the article is the chemical itself, would provide better insight into dosing, whether the fungus is the carrier or otherwise. 2603:900A:1AF0:93D0:8A9:8721:58D9:40BE (talk) 20:41, 2 October 2023 (UTC)[reply]

McCarry's synthesis

the synthesis using ethylchloroformate is incorrectly represented as using ethylacetate (that is it misses a chlorine in place of a methyl). Alas the picture is not editable as such and, since former schemes drawn with chemsketch had been refused to me before, I will no longer try to directly edit it. SGRPB7 (talk) 00:33, 20 July 2024 (UTC)[reply]

Made up sources?

As best I can tell, there are 14 made up sources in this article. I tagged them all with "verification needed". Maybe the bibliographic info is messed up and something with slightly different authors, title or whatever actually does exist. But right now, it looks like these were completely made up. — Chris Capoccia 💬 19:17, 20 July 2024 (UTC)[reply]

Back in June a user named James Johnsoniuk did a massive amount of additions and rewrites, and I believe he is responsible for most or all of those. Someone noted that the entire Effects section looks like it was written using an AI, and I have to agree. It may be best to revert all of their changes. Zephandrypus (talk) 22:57, 1 August 2024 (UTC)[reply]