Talk:Tilorone
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chembox
[edit]I'm having trouble with the chem box, if you know how to use it- please do. oh.. citing, help me by adding the citation - the information above is from the merck index, 13th edition p.1683 If you have a picture of the molecule, add it- its a nice one looks like a temple for the oxygen built by cyclic and aromatic ligands very unique . If you feel like formalizing this page using the traditional wiki way (adding "stub" boxes and "lacks citations" boxes etc' ), go ahead.
history
[edit]cut from article and pasted here - needs sourcing and copyediting:
Tilorone was developed in the 1970s by the RICHARDSON MERRELL INC (US Patent 3592819, Filed Dec. 30, 1968, Ser. No. 788,038) and resynthesized in the USSR in the Physico-Chemical Institute of the Academy of Sciences of UkrSSR by Ludmila A. Litvinova and coworkers ( 1975-1976). In the USSR it's antiviral and interferon inducing properties were investigated in the DI Ivanovski Institute of virology AMS (Moscow) by Felix I. Ershov and coworkers (1980 - 1986) resulted with 1st phase clinical trials in 1987-1988 (anti-HAV, Moscow), 2nd phase clinical trials in 1989-1991 (anti influenza), 3rd phase 1993 - 1995. In 1996 it was approved by Pharmacological committee of RF for the viral infections therapeutics and prophylaxis (flu, hepatitis A, B, herpes simplex). It has been widely used in Ukraine since March 2005. It is produced by InterChem, based in Odessa.